Publication Title Authors Publication Year Sort ascending
Enzyme promiscuity shapes adaptation to novel growth substrates

Guzmán GI, Sandberg TE, LaCroix RA, Nyerges Á, Papp H, de Raad M, King ZA,
Hefner Y, Northen TR, Notebaart RA, Pál C, Palsson BO, Papp B, Feist AM

2019
The genetic basis for adaptation of model-designed syntrophic co-cultures

Lloyd CJ, King ZA, Sandberg TE, Hefner Y, Olson CA, Phaneuf PV, O'Brien EJ, Sanders JG, Salido RA, Sanders K, Brennan C, Humphrey G, Knight R, Feist AM

2019
Cross-compartment metabolic coupling enables flexible photoprotective mechanisms in the diatom Phaeodactylum tricornutum

Broddrick JT, Du N, Smith SR, Tsuji Y, Jallet D, Ware MA, Peers G, Matsuda Y, 
Dupont CL, Mitchell BG, Palsson BO, Allen AE

2019
Evolution and regulation of nitrogen flux through compartmentalized metabolic networks in a marine diatom

Smith SR, Dupont CL, McCarthy JK, Broddrick JT, Oborník M, Horák A, Füssy Z, Cihlář J, Kleessen S, Zheng H, McCrow JP, Hixson KK, Araújo WL, Nunes-Nesi A, Fernie A, Nikoloski Z, Palsson BO, Allen AE

2019
Adaptive laboratory evolution of a genome-reduced Escherichia coli

D. Choe; J.Hyoung Lee; M. Yoo; S. Hwang; B.Hyun Sung; S. Cho; B. Palsson; S.Chang Kim; B.K. Cho

2019
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action

Yang, J.H., Wright, S.N., Hamblin, M., McCloskey, D., Alcantar, M.A., Schrubbers, L., Lopatkin, A.J., Satish, S., Nili, A., Palsson, B.O., Walker, G.C., Collins, J.J

2019
Adaptive laboratory evolution of Escherichia coli under acid stress

Du B, Olson CA, Sastry AV, Fang X, Phaneuf PV, Chen K, Wu M, Szubin R, Xu S, Hefner Y, Feist AM, Palsson BO

2019
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance

E.S. Kavvas; E. Catoiu; N. Mih; J.T. Yurkovich; Y. Seif; N. Dillon; D. Heckmann; A. Anand; L. Yang; V. Nizet; J.M. Monk; B.O. Palsson

2018
Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing.

J.Seong Lee; J.Hyoung Park; T.Kwang Ha; M. Samoudi; N.E. Lewis; B.O. Palsson; H.Faustrup Kildegaard; G.M. Lee

2018
Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow

E. Brunk; R.L. Chang; J. Xia; H. Hefzi; J.T. Yurkovich; D. Kim; E. Buckmiller; H.H. Wang; B.K. Cho; C. Yang; B.O. Palsson; G.M. Church; N.E. Lewis

2018
Temperature-Dependent Estimation of Gibbs Energies Using an Updated Group-Contribution Method.

B. Du; Z. Zhang; S. Grubner; J.T. Yurkovich; B.O. Palsson; D.C. Zielinski

2018
Dataset on economic analysis of mass production of algae in LED-based photobioreactors.

W. Fu; S. Gudmundsson; K. Wichuk; S. Palsson; B.O. Palsson; K. Salehi-Ashtiani; S. Brynjólfsson

2018
Thermodynamic favorability and pathway yield as evolutionary tradeoffs in biosynthetic pathway choice

B. Du; D.C. Zielinski; J.M. Monk; B.O. Palsson

2018
The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

K.S. Choudhary; N. Mih; J. Monk; E. Kavvas; J.T. Yurkovich; G. Sakoulas; B.O. Palsson

2018
Systems analysis of metabolism in platelet concentrates during storage in platelet additive solution.

F. Johannsson; S. Guðmundsson; G. Paglia; S. Guðmundsson; B. Palsson; O.E. Sigurjónsson; O. Rolfsson

2018
ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions.

H. Latif; S. Federowicz; A. Ebrahim; J. Tarasova; R. Szubin; J. Utrilla; K. Zengler; B.O. Palsson

2018
Escher-FBA: a web application for interactive flux balance analysis

E. Rowe; B.O. Palsson; Z.A. King

2018
High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli.

S. Cho; D. Choe; E. Lee; S.Chang Kim; B. Palsson; B.K. Cho

2018
Basics of genome-scale metabolic modeling and applications on C1-utilization.

I. Kabimoldayev; A.Duc Nguyen; L. Yang; S. Park; E.Yeol Lee; D. Kim

2018
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE

C.J. Norsigian; E. Kavvas; Y. Seif; B.O. Palsson; J.M. Monk

2018
Reframing gene essentiality in terms of adaptive flexibility.

G.I. Guzman; C.A. Olson; Y. Hefner; P.V. Phaneuf; E. Catoiu; L.B. Crepaldi; L.Goldschmid Micas; B.O. Palsson; A.M. Feist

2018
Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits.

Y. Seif; E. Kavvas; J.C. Lachance; J.T. Yurkovich; S.P. Nuccio; X. Fang; E. Catoiu; M. Raffatellu; B.O. Palsson; J.M. Monk

2018
Laboratory evolution reveals regulatory and metabolic trade-offs of glycerol utilization in Saccharomyces cerevisiae.

T. Strucko; K. Zirngibl; F. Pereira; E. Kafkia; E.T. Mohamed; M. Rettel; F. Stein; A.M. Feist; P. Jouhten; K.Raosaheb Patil; J. Forster

2018
ALEdb 1.0: a database of mutations from adaptive laboratory evolution experimentation.

P.V. Phaneuf; D. Gosting; B.O. Palsson; A.M. Feist

2018
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Systems biology as an emerging paradigm in transfusion medicine.

J.T. Yurkovich; A. Bordbar; O.E. Sigurjónsson; B.O. Palsson

2018
Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

D. Heckmann; D.C. Zielinski; B.O. Palsson

2018
Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in knockout evolutions.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions.

E.S. Kavvas; Y. Seif; J.T. Yurkovich; C. Norsigian; S. Poudel; W.W. Greenwald; S. Ghatak; B.O. Palsson; J.M. Monk

2018