Publication Title Authors Publication Year Sort ascending
High-quality genome-scale metabolic modeling of Pseudomonas putida highlights its broad metabolic capabilities

Nogales J, Mueller J, Gudmundsson S, Canalejo FJ, Duque E, Monk J, Feist AM, Ramos JL, Niu W, Palsson BO

2019
Primary transcriptome and translatome analysis determines transcriptional and translational regulatory elements encoded in the Streptomyces clavuligerus genome

Hwang S, Lee N, Jeong Y, Lee Y, Kim W, Cho S, Palsson BO, Cho BK

2019
Adaptive evolution reveals a tradeoff between growth rate and oxidative stress during naphthoquinone-based aerobic respiration

Anand A, Chen K, Yang L, Sastry AV, Olson CA, Poudel S, Seif Y, Hefner Y, Phaneuf PV, Xu S, Szubin R, Feist AM, Palsson BO

2019
The y-ome defines the 35% of Escherichia coli genes that lack experimental evidence of function

S. Ghatak; Z.A. King; A. Sastry; B.O. Palsson

2019
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism

Cheng C, O'Brien EJ, McCloskey D, Utrilla J, Olson C, LaCroix RA, Sandberg TE, Feist AM, Palsson BO, King ZA

2019
Expanding the uses of genome‐scale models with protein structures

Mih N and Palsson BO

2019
Escher-FBA: a web application for interactive flux balance analysis

E. Rowe; B.O. Palsson; Z.A. King

2018
High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli.

S. Cho; D. Choe; E. Lee; S.Chang Kim; B. Palsson; B.K. Cho

2018
Basics of genome-scale metabolic modeling and applications on C1-utilization.

I. Kabimoldayev; A.Duc Nguyen; L. Yang; S. Park; E.Yeol Lee; D. Kim

2018
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE

C.J. Norsigian; E. Kavvas; Y. Seif; B.O. Palsson; J.M. Monk

2018
Reframing gene essentiality in terms of adaptive flexibility.

G.I. Guzman; C.A. Olson; Y. Hefner; P.V. Phaneuf; E. Catoiu; L.B. Crepaldi; L.Goldschmid Micas; B.O. Palsson; A.M. Feist

2018
Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits.

Y. Seif; E. Kavvas; J.C. Lachance; J.T. Yurkovich; S.P. Nuccio; X. Fang; E. Catoiu; M. Raffatellu; B.O. Palsson; J.M. Monk

2018
Laboratory evolution reveals regulatory and metabolic trade-offs of glycerol utilization in Saccharomyces cerevisiae.

T. Strucko; K. Zirngibl; F. Pereira; E. Kafkia; E.T. Mohamed; M. Rettel; F. Stein; A.M. Feist; P. Jouhten; K.Raosaheb Patil; J. Forster

2018
ALEdb 1.0: a database of mutations from adaptive laboratory evolution experimentation.

P.V. Phaneuf; D. Gosting; B.O. Palsson; A.M. Feist

2018
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Systems biology as an emerging paradigm in transfusion medicine.

J.T. Yurkovich; A. Bordbar; O.E. Sigurjónsson; B.O. Palsson

2018
Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

D. Heckmann; D.C. Zielinski; B.O. Palsson

2018
Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in knockout evolutions.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions.

E.S. Kavvas; Y. Seif; J.T. Yurkovich; C. Norsigian; S. Poudel; W.W. Greenwald; S. Ghatak; B.O. Palsson; J.M. Monk

2018
Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

D. Heckmann; C.J. Lloyd; N. Mih; Y. Ha; D.C. Zielinski; Z.B. Haiman; A.Amer Desouki; M.J. Lercher; B.O. Palsson

2018
Systematic discovery of uncharacterized transcription factors in Escherichia coli K-12 MG1655.

Y. Gao; J.T. Yurkovich; S.Woo Seo; I. Kabimoldayev; A. Dräger; K. Chen; A.V. Sastry; X. Fang; N. Mih; L. Yang; J. Eichner; B.K. Cho; D. Kim; B.O. Palsson

2018
Recon3D enables a three-dimensional view of gene variation in human metabolism.

E. Brunk; S. Sahoo; D.C. Zielinski; A. Altunkaya; A. Dräger; N. Mih; F. Gatto; A. Nilsson; G.Andres Pre Gonzalez; M.Kathrin Aurich; A. Prlić; A. Sastry; A.D. Danielsdottir; A. Heinken; A. Noronha; P.W. Rose; S.K. Burley; R.M.T. Fleming; J. Nielsen; I. Thiele; B.O. Palsson

2018
Gapless, Unambiguous Genome Sequence for Escherichia coli C, a Workhorse of Industrial Biology

J.E. Pekar; P. Phaneuf; R. Szubin; B. Palsson; A. Feist; J.M. Monk

2018
Network-level allosteric effects are elucidated by detailing how ligand-binding events modulate utilization of catalytic potentials.

J.T. Yurkovich; M.A. Alcantar; Z.B. Haiman; B.O. Palsson

2018
ssbio: A Python Framework for Structural Systems Biology

N. Mih; E. Brunk; K. Chen; E. Catoiu; A. Sastry; E. Kavvas; J.M. Monk; Z. Zhang; B.O. Palsson

2018
Predicting the metabolic capabilities of Synechococcus elongatus PCC 7942 adapted to different light regimes.

J.T. Broddrick; D.G. Welkie; D. Jallet; S.S. Golden; G. Peers; B.O. Palsson

2018
A unified resource for transcriptional regulation in Escherichia coli K-12 incorporating high-throughput-generated binding data into RegulonDB version 10.0

A. Santos-Zavaleta; M. Sánchez-Pérez; H. Salgado; D.A. Vázquez-Ramírez; S. Gama-Castro; V.H. Tierrafría; S.J.W. Busby; P. Aquino; X. Fang; B.O. Palsson; J.E. Galagan; J. Collado-Vides

2018
Systems assessment of transcriptional regulation on central carbon metabolism by Cra and CRP.

D. Kim; S.Woo Seo; Y. Gao; H. Nam; G.I. Guzman; B.K. Cho; B.O. Palsson

2018
Sugar-stimulated CO2 sequestration by the green microalga Chlorella vulgaris

W. Fu; S. Gudmundsson; K. Wichuk; S. Palsson; B.O. Palsson; K. Salehi-Ashtiani; ður ólfsson

2018
Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018