Publication Title Authors Publication Year Sort ascending
Systems-level analysis of NalD mutation, a recurrent driver of rapid drug resistance in acute Pseudomonas aeruginosa infection

Yan J, Estanbouli H, Liao C, Kim W, Monk JM, Rahman R, Kamboj M, Palsson BO, Qiu W, Xavier JB

2019
DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression

Yang L, Ebrahim A, Lloyd CJ, Saunders MA, Palsson BO

2019
Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of Escherichia coli During Adaptive Laboratory Evolution

Kang M, Kim K, Choe D, Cho S, Kim SC, Palsson B, Cho BK

2019
A workflow for generating multi-strain genome-scale metabolic models of prokaryotes

Norsigian CJ, Fang X, Seif Y, Monk JM, Palsson BO

2019
Sugar-stimulated CO2 sequestration by the green microalga Chlorella vulgaris

W. Fu; S. Gudmundsson; K. Wichuk; S. Palsson; B.O. Palsson; K. Salehi-Ashtiani; ður ólfsson

2018
Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance.

D. Choe; R. Szubin; S. Dahesh; S. Cho; V. Nizet; B. Palsson; B.K. Cho

2018
Metagenomics-Based, Strain-Level Analysis of Escherichia coli From a Time-Series of Microbiome Samples From a Crohn's Disease Patient

X. Fang; J.M. Monk; S. Nurk; M. Akseshina; Q. Zhu; C. Gemmell; C. Gianetto-Hill; N. Leung; R. Szubin; J. Sanders; P.L. Beck; W. Li; W.J. Sandborn; S.D. Gray-Owen; R. Knight; E. Allen-Vercoe; B.O. Palsson; L. Smarr

2018
COBRAme: A computational framework for genome-scale models of metabolism and gene expression.

C.J. Lloyd; A. Ebrahim; L. Yang; Z.A. King; E. Catoiu; E.J. O'Brien; J.K. Liu; B.O. Palsson

2018
Quantitative -omic data empowers bottom-up systems biology

J.T. Yurkovich; B.O. Palsson

2018
Estimating Metabolic Equilibrium Constants: Progress and Future Challenges

B. Du; D.C. Zielinski; B.O. Palsson

2018
Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Modeling the multi-scale mechanisms of macromolecular resource allocation

L. Yang; J.T. Yurkovich; Z.A. King; B.O. Palsson

2018
Identification of growth-coupled production strains considering protein costs and kinetic variability

H.V. Dinh; Z.A. King; B.O. Palsson; A.M. Feist

2018
Escherichia coli B2 strains prevalent in inflammatory bowel disease patients have distinct metabolic capabilities that enable colonization of intestinal mucosa.

X. Fang; J.M. Monk; N. Mih; B. Du; A.V. Sastry; E. Kavvas; Y. Seif; L. Smarr; B.O. Palsson

2018
Functional interrogation of Plasmodium genus metabolism identifies species- and stage-specific differences in nutrient essentiality and drug targeting.

A.M. Abdel-Haleem; H. Hefzi; K. Mineta; X. Gao; T. Gojobori; B.O. Palsson; N.E. Lewis; N. Jamshidi

2018
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance

E.S. Kavvas; E. Catoiu; N. Mih; J.T. Yurkovich; Y. Seif; N. Dillon; D. Heckmann; A. Anand; L. Yang; V. Nizet; J.M. Monk; B.O. Palsson

2018
Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes.

D. McCloskey; S. Xu; T.E. Sandberg; E. Brunk; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2018
Revealing Key Determinants of Clonal Variation in Transgene Expression in Recombinant CHO Cells Using Targeted Genome Editing.

J.Seong Lee; J.Hyoung Park; T.Kwang Ha; M. Samoudi; N.E. Lewis; B.O. Palsson; H.Faustrup Kildegaard; G.M. Lee

2018
Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow

E. Brunk; R.L. Chang; J. Xia; H. Hefzi; J.T. Yurkovich; D. Kim; E. Buckmiller; H.H. Wang; B.K. Cho; C. Yang; B.O. Palsson; G.M. Church; N.E. Lewis

2018
Temperature-Dependent Estimation of Gibbs Energies Using an Updated Group-Contribution Method.

B. Du; Z. Zhang; S. Grubner; J.T. Yurkovich; B.O. Palsson; D.C. Zielinski

2018
Dataset on economic analysis of mass production of algae in LED-based photobioreactors.

W. Fu; S. Gudmundsson; K. Wichuk; S. Palsson; B.O. Palsson; K. Salehi-Ashtiani; S. Brynjólfsson

2018
Thermodynamic favorability and pathway yield as evolutionary tradeoffs in biosynthetic pathway choice

B. Du; D.C. Zielinski; J.M. Monk; B.O. Palsson

2018
The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

K.S. Choudhary; N. Mih; J. Monk; E. Kavvas; J.T. Yurkovich; G. Sakoulas; B.O. Palsson

2018
Systems analysis of metabolism in platelet concentrates during storage in platelet additive solution.

F. Johannsson; S. Guðmundsson; G. Paglia; S. Guðmundsson; B. Palsson; O.E. Sigurjónsson; O. Rolfsson

2018
ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions.

H. Latif; S. Federowicz; A. Ebrahim; J. Tarasova; R. Szubin; J. Utrilla; K. Zengler; B.O. Palsson

2018
Escher-FBA: a web application for interactive flux balance analysis

E. Rowe; B.O. Palsson; Z.A. King

2018
High-Level dCas9 Expression Induces Abnormal Cell Morphology in Escherichia coli.

S. Cho; D. Choe; E. Lee; S.Chang Kim; B. Palsson; B.K. Cho

2018
Basics of genome-scale metabolic modeling and applications on C1-utilization.

I. Kabimoldayev; A.Duc Nguyen; L. Yang; S. Park; E.Yeol Lee; D. Kim

2018
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE

C.J. Norsigian; E. Kavvas; Y. Seif; B.O. Palsson; J.M. Monk

2018